Aging Human

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NAD+

Nicotinamide Adenine Dinucleotide
Many types of NAD+ Therapies are emerging, of which, many are all-natural, holistic, and some have shown outstanding results in many animal studies and anecdotal human accounts. NAD+ Therapy may be the light at the end of the tunnel for many people suffering from the complexities of lowering vitality and aging.  However, other than the many animal studies and a large amount of positive anecdotal accounts from humans there are no human studies to learn from, yet.  

There are multiple ways to increase NAD+ in the body.  It appears that mild stress to some of the systems in the body will cause the creation of NAD+.  Fasting, low calorie consumption, cold and possibly hot temperature exposure, exercise, some foods more than others, and more.  The vitamin and supplement options include NAD+, which comes in multiple forms, the precursor to NAD+, NMN ( Nicotinamide MonoNucleotide ), and the precursor to NMN, NR ( Nicotinamide Riboside ).  All of which are downstream of Niacin.
More NAD+ Research is Needed
At this time we are unaware of any studies being conducted nor planned that will measure the health impact of longterm optimal NAD+ levels in humans.  The reasons for this are not clear but regardless, the thought leaders are continuing to create nutrients and eventually drugs that will increase NAD+ levels.  It would be difficult to reasonably dismiss the benefits of optimal NAD+ levels while having the knowledge of well financed scientists at prestigious universities around the world are working to develop treatments and drugs to optimally increase NAD+ levels in humans.  Undoubtably, the intersection of business and longevity will continue to make for some murky waters for the foreseeable future.  

It is up to all of us to educate ourselves and work towards improving our lifestyle choices and improving what we put into our bodies based on the best information we can find for each of us.  Considering the time constraints we all are under and the progress of actionable information from the scientific community it seems wise to conduct educated and measured research on ourselves.
Click here to check out this short video on NAD+ in action.
A Little More About NAD+
NAD+ is found in every living cell and as the cell ages it produces less NAD+. NAD+ is required in over 400 known processes in the body and if all NAD+ disappeared in a living creature they would die within 30 seconds. There are seemingly competing reasons why the cell makes less NAD+ over time. Aging with the definition being from DNA information quality degradation or drift as proposed by Dr David Sinclair in his book Lifespan. And/or oxidative stress is thought to contribute to lowering cellular NAD+ levels.

It has been discovered our NAD+ levels decline over time which may be a factor in aging and illness [PubMed].  There is a body of work that has connected low NAD+ to conditions such as aging, may increase the likelihood of sun burns, fatigue, possibly associated with weight gain and metabolic syndrome, may worsen cardiovascular diseases, may contribute to multiple sclerosis, decreases cellular antioxidants, decreases metabolism, may impair brain function, may harm immune balance, and even may increase inflammation.  Considering the massive number of processes the body needs NAD+ for we expect that many more conditions will be discovered to be related to a less than optimal amount of NAD+.
Click here for a more in depth write up with study references from SelfHacked.com.

3 Versions of NMN

Everyone is different so AgingHuman offers you three ways to get NMN into your body.

NMN CAPSULES

AgingHuman NMN capsules are great for the person that would like to take 300 mg with the ease of capsules.  Each bottle will contain a 30 count of capsules.

NMN & TMG CAPSULES

TMG is thought to help maximize the uptake of NMN so we added it to our capsule offering...

NMN POWDER

For the value conscious consumer, AgingHuman offers a powder form NMN.  Each container will have 10 grams of NMN powder.
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Raising NAD+
  There are multiple ways to raise NAD+ levels, including what are called precursors. A precursor, for NAD+, is usually taken orally, but sometimes taken sublingually, and some of precursor will be converted by the body into intracellular NAD+.  As referenced above, precursors to NAD+, NMN and NR, have been shown to raise NAD+ levels in animals with NR being researched more extensively. 

There is another way to get more NAD+ into the body by using the molecule NAD+.  Again, there are no known studies on raising NAD+ in humans by using NAD+.  However, clinics treating a wide range of conditions sometimes use intravenous NAD+, sublingual, and subcutaneous NAD+, subQ NAD+, to administer NAD+ directly into the patient.  

All of the intravenous and injectable vitamins sold by AgingHuman are NOT for human consumption, but for research purposes only.  AgingHuman will not provide advice with any NAD+ stacks that include injectable vitamins and nutrients.  All injectable forms of vitamins and nutrients are for research purposes only.

In an effort to raise NAD+ nasal sprays, sublingual, and subQ administration of NAD+ are now available.  Please consider there are no patents on NAD+ so it seems unlikely there will be any studies on how much of the bodies levels of NAD+ will rise per administration method and dose.  This is one of the other murky water areas of longevity science.  
NAD+ Stacks
A stack, in this context, is a system or a protocol that usually combines activities, habits, vitamins / nutrients, delivery methods of vitamins / nutrients, timings of activities and delivery of vitamins / nutrients, any other new and consistent changes that can be measured that contribute towards the desired result.  As stated above, there are many activities and supplements that can raise NAD+ levels but there is very little understanding of the value of combining these different activities and supplements or what each will accomplish.  Surely there will be better and worse NAD+ stacks to raise NAD+ to optimal levels but determining which is best will be an individual effort until many reliable studies have been completed and comparisons can be made.

To determine the best NAD+ raising stack there is a lot to consider. The NAD+ stack you decide to use will be a personal decision and would serve you best if you document what the goal is, what metrics will be used, and a timeframe.  Then, track any measurable changes you can before, during, and after the protocol is used.  After multiple stacks have been measured those results can be compared and you will be in a better position to refine the NAD+ stack to get optimal results for you.
  If you have any questions just reach out to us, the contact link is at the bottom of the page, we would be more than happy to help.  Although we will not offer dosing suggestions for injectable vitamins and nutrients we can answer questions about the high quality ingredients we use, special shipping requirements, and for other resources concerning the benefits of increasing NAD+.

For more information and people talking about the impact of increasing NAD+ follow the link below.
Click here to listen to Ben Greenfield interview researchers and physicians about NAD+.
What is Glutathione?
Glutathione is an antioxidant in plants, animals, fungi, and some bacteria and archaea. Glutathione is capable of preventing damage to important cellular components caused by reactive oxygen species such as free radicals, peroxides, lipid peroxides, and heavy metals.

What are the health benefits of Glutathione?

- Reduces oxidative stress.

- May improve psoriasis.

- Reduces cell damage in alcoholic and nonalcoholic fatty liver disease.

-Improves insulin resistance in older individuals.

- Increases mobility for people with peripheral artery disease.

- Reduces symptoms of Parkinson's disease.

- May help fight against autoimmune disease.
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*** IMPORTANT MESSAGE ***

Read this before ordering
We are very small company with a small staff. All products are made to order. We do not pre-make items. Your order will ship within 5 business days, and once we ship it, you will be given a tracking number.
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